Definition of Prestin
Prestin is a protein that is critical to sensitive hearing in mammals. It is encoded by the SLC26A5 (solute carrier anion transporter family 26, member 5) gene.
Different variants of this protein are known in the animal world, all involved in hearing or echolocation.
Prestin is the motor protein of the outer hair cells of the inner ear of the mammalian cochlea. It is highly expressed in the outer hair cells, and is not expressed in the nonmotile inner hair cells. Immunolocalization shows prestin is expressed in the lateral plasma membrane of the outer hair cells, the region where electromotility occurs. The expression pattern correlates with the appearance of outer hair cell electromotility.
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Frequently asked questions
What is Prestin?
Prestin is a protein that is critical to sensitive hearing in mammals. It is encoded by the SLC26A5 (solute carrier anion transporter family 26, member 5) gene.
Sources & credits
- Wikipedia: Prestin – CC BY-SA 4.0
- Image by National Center for Biotechnology Information, U.S. National Library of Medicine – Public domain