Definition of Transcranial focused ultrasound
Transcranial focused ultrasound (tFUS), also known as transcranial ultrasound stimulation (TUS) or low-intensity focused ultrasound (LIFU), is a form of focused ultrasound (FUS) which is being investigated for the potential non-invasive treatment of psychiatric and neurological disorders. It has also been used as a tool to investigate causal effects of tFUS targeting subcortical brain structures in humans. It differs from other non-invasive brain stimulation methods such as magnetic (transcranial magnetic stimulation or TMS) and electrical (transcranial direct-current stimulation or tDCS) in that it has higher spatial resolution and precision (millimetric) and is able to reach deep brain structures. Depending on the parameters, tFUS can inhibit, stimulate, and even ablate brain tissue. Only a handful of clinical studies of tFUS for psychiatric conditions have been conducted as of 2024.
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Frequently asked questions
What is Transcranial focused ultrasound?
Transcranial focused ultrasound (tFUS), also known as transcranial ultrasound stimulation (TUS) or low-intensity focused ultrasound (LIFU), is a form of focused ultrasound (FUS) which is being investigated for the potential non-invasive treatment of…